Synthetic Cannabinoids
4F-ADB
Street names: 4F-MDMB-BUTINACA
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Cannabis-like high but far more intense — sedation, confusion, anxiety
⚠Key risks
- Associated with 'Spice zombies' — catatonia, seizures
- Unpredictable potency sprayed unevenly
- Kidney damage, heart rhythm problems
✚Overdose signs
- Severe agitation, psychosis
- Seizures
- Racing heart, vomiting
📋Quick facts
Also known as4F-MDMB-BUTINACA
CategorySynthetic Cannabinoids
Schedule / classSchedule I (US, 2021)
AppearanceWhite/yellow powder sprayed onto plant material ('K2/Spice') or in vape carts
Street price~$5–$20 per gram of 'herbal blend'
Legal statusSchedule I (US); banned UK/CA/AU/EU-wide
Last updated2026-09-12
Sources: DEA, EMCDDA, NPS-AD
Category comparison — Synthetic Cannabinoids
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| 4F-ADB | Schedule I | Associated with 'Spice zombies' — catatonia, seizures; Unpredictable potency sprayed unevenly | ~$5–$20 per gram of 'herbal blend' |
| 5F-ADB / 5F-ADBICA | Schedule I | Multiple deaths linked to 5F-ADB (the compound behind early 'zombie spice' outbreaks); Seizures, kidney injury | ~$5–$20 per gram of blend |
| JWH-250 | Schedule I | First-generation spice compound; contaminated batches caused outbreaks; Anxiety, tachycardia | ~$5–$15 per gram of blend |
| NM-2201 (CBL-2201) | Analogue prosecutions | Little human data; Severe anxiety, seizures reported | ~$5–$20 per gram of blend |
Street prices are regional estimates. Potency and cuts vary constantly — see our pressed pill guide.
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Profiles are reviewed against NIDA/DEA/EMCDDA sources. See something off? Submit a correction — it goes straight to our editorial queue.