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22 substances

Opioids

Heroin, fentanyl, painkillers and the nitazenes — the deadliest category in the drug supply. Opioids suppress breathing. Most overdose deaths in the US, Canada and Europe now involve fentanyl or its analogues — often mixed into drugs the buyer never asked for.

~80%of US overdose deaths involve an opioid (CDC)
22profiles in this category
Schedule I

Heroin

White/off-white powder (US) or brown base powder ('sugar brown'); black tar (Mexico)

Effects & risks →
Schedule II

Fentanyl

White powder, pressed pills, counterfeit oxycodone — often invisible when mixed into other drugs

Effects & risks →
Schedule II / analogue prosecutions

Fentanyl HCl (powder)

Fine white crystalline powder, indistinguishable from other white powders

Effects & risks →
Schedule I

Acetylfentanyl

White/tan powder, sometimes sold as 'synthetic heroin' or pressed into pills

Effects & risks →
Schedule I

Furanylfentanyl (Fu-F)

White/yellowish powder or pressed tablets

Effects & risks →
Schedule I

Methoxyacetylfentanyl

White/off-white powder

Effects & risks →
Schedule I

Etonitazene

White/yellow/off-white powder, pills, or e-liquid for vaping

Effects & risks →
Emerging — prosecuted as analogue

Isotodesnitazene

White/yellow powder, often mixed into heroin or counterfeit pills

Effects & risks →
Schedule II

Oxymorphone (Opana 40 mg)

Pink/octagonal ER tablets (Opana 40 mg); white IR tablets

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Schedule II

Morphine 60 mg

Round ER tablets imprinted 60 (purple/orange by brand); oral solution; injectable ampoules

Effects & risks →
Schedule II

Hydromorphone (Dilaudid 8 mg)

Small triangular white tablets ('8mg triangles'); clear injectable liquid

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Schedule II

Oxycodone (Roxicodone 30 mg)

Blue 30 mg IR tablets; also white pills with various imprints

Effects & risks →
Schedule II

OxyContin

Round ER tablets (OC imprint); reformulated 2010 to deter crushing

Effects & risks →
Schedule V / Rx

Codeine 30/500 mg (co-codamol)

White tablets (30 mg codeine / 500 mg paracetamol); purple/clear syrup

Effects & risks →
Schedule II

Hydrocodone 10/500 mg

White/oblong tablets imprinted Watson 540-style; capsules historically

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Schedule II

Hydrocodone–Ibuprofen (Vicoprofen)

White oblong tablets (7.5 mg hydro / 200 mg ibuprofen)

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Schedule II

Meperidine (Demerol)

White capsules (50/100 mg); clear injectable solution

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Schedule II

Methadone

Orange/red diskettes (40 mg), liquid (cherry), tablets, injectable ampoules

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Schedule III

Suboxone (buprenorphine/naloxone)

Orange sublingual films (2/0.5 mg, 8/2 mg) or hexagonal tablets

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Schedule III

Subutex (buprenorphine)

White sublingual tablets (2 mg, 8 mg), hexagonal imprint

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Schedule II

Fentanyl patches (Duragesic 12.5 mcg/hr)

Tan rectangular transdermal patches (12.5–100 mcg/hr), gel or matrix type

Effects & risks →
Not a controlled drug — veterinary anesthetic, adulterant

Xylazine (Tranq)

No street form of its own — found mixed into fentanyl/heroin (white/beige powder) or pills

Effects & risks →