Performance & Grey-Market Pharma
AICAR (Acadesine)
Street names: AICA ribonucleotide, GW501516's twin (grey market)
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- AMPK activator — increases endurance at cellular level (animal data only)
⚠Key risks
- No human safety data — cancer-risk flags in cell studies
- Sold as research chemical, zero quality control
✚Overdose signs
- Unknown in humans
- Potential hypoglycemia symptoms
📋Quick facts
Also known asAICA ribonucleotide, GW501516's twin (grey market)
CategoryPerformance & Grey-Market Pharma
Schedule / classUnscheduled (US/EU) — banned by WADA
AppearanceWhite powder, sold as 'exercise in a pill' grey-market research chemical
Street price~$50–$150 per gram (grey market)
Legal statusUnscheduled but not approved for human use; prohibited in sport (WADA)
Last updated2026-09-12
Sources: WADA, PubMed
Category comparison — Performance & Grey-Market Pharma
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| AICAR (Acadesine) | Unscheduled | No human safety data — cancer-risk flags in cell studies; Sold as research chemical, zero quality control | ~$50–$150 per gram |
| Clenbuterol HCl | Not approved for human use | Racing heart, arrhythmia, tremors; Overdose: dangerous potassium shifts, cardiac events | ~$0.50–$2 per 40 mcg tablet |
| Anastrozole (Arimidex) | Rx-only | Bone density loss, joint pain with long-term use; Crash estrogen too low → depression, libido loss | ~$2–$8 per 1 mg tablet |
| Tadalafil (Cialis) | Rx-only — not controlled | Counterfeit ED pills are a major fentanyl/adulterant channel in some regions; Dangerous blood pressure drop with nitrates | ~$2–$15 per tablet |
Street prices are regional estimates. Potency and cuts vary constantly — see our pressed pill guide.
Spotted wrong or outdated info?
Profiles are reviewed against NIDA/DEA/EMCDDA sources. See something off? Submit a correction — it goes straight to our editorial queue.