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Opioids

Methadone

Street names: Done, Dolly, Amidone

Methadone — Orange/red diskettes (40 mg), liquid (cherry), tablets, injectable ampoules

What it does

  • Long-lasting (24–36 h) opioid stability, blocks withdrawal and cravings

Key risks

  • Accumulates over days — overdose risk highest in first 2 weeks
  • Fatal mixing with benzos/alcohol

Overdose signs

  • Pinpoint pupils
  • Slow breathing
  • Extreme sedation

📋Quick facts

Also known asDone, Dolly, Amidone
CategoryOpioids
Schedule / classSchedule II (US)
AppearanceOrange/red diskettes (40 mg), liquid (cherry), tablets, injectable ampoules
Street price~$10–$40 per 40 mg diskette (diverted)
Legal statusRx via licensed opioid-treatment programs; diversion is a felony
Last updated2026-09-12
Sources: SAMHSA, NIDA, DEA

Category comparison — Opioids

SubstanceClassTop risksStreet price
MethadoneSchedule IIAccumulates over days — overdose risk highest in first 2 weeks; Fatal mixing with benzos/alcohol~$10–$40 per 40 mg diskette
HeroinSchedule IExtremely addictive — physical dependence in weeks; Overdose: breathing slows or stops~$10–$40 per bag
FentanylSchedule IIRespiratory depression; Addiction in days~$20–$40 per counterfeit pill
Fentanyl HCl (powder)Schedule II / analogue prosecutionsLab-purity powder is far stronger than street mixes; Weighing errors are fatal~$60–$120/gram wholesale equivalent
AcetylfentanylSchedule I~5–15× weaker than fentanyl but still deadly at gram-level mistakes; Frequent cause of cluster overdoses~$25–$60/g where found
Furanylfentanyl (Fu-F)Schedule ILinked to hundreds of fatal overdoses 2016–2018; Potency similar to fentanyl~$20–$50/g
Street prices are regional estimates. Potency and cuts vary constantly — see our pressed pill guide.